Association of homocysteinaemia with hyperglycaemia, dyslipidaemia, hypertension and obesity
نویسندگان
چکیده
AIM Hyperhomocysteinaemia and the metabolic syndrome are associated with increased cardiovascular risk. We investigated whether there is a link between the metabolic syndrome or its components and homocysteine levels in a population without cardiovascular disease. METHODS From the population sample of 382 participants (286 females and 96 males) we isolated those reflecting the metabolic syndrome and determined their homocysteine levels. We then evaluated the association of homocysteine with hyperglycaemia, hypertriglyceridaemia, hypercholesterolaemia, hypertension and obesity, using a significance level of p = 0.05. Enzymatic methods were used for all biochemical parameters. RESULTS We found the statistical relationship between homocysteine and the metabolic syndrome as follows: hyperglycaemia (p = 0.175), hypertriglyceridaemia (p = 0.442), hypercholesterolaemia (p = 0.480), obesity (p = 0.080); and hypertension: systolic pressure (p = 0.002) and diastolic pressure (p = 0.033). CONCLUSION We found no statistically significant association between baseline plasma homocysteine levels and the metabolic syndrome, except for hypertension.
منابع مشابه
Prevalences of overweight, obesity, hyperglycaemia, hypertension and dyslipidaemia in the Gulf: systematic review
OBJECTIVES To examine the prevalence of risk factors for diabetes and its complications in the Co-operation Council of the Arab States of the Gulf (GCC) region. DESIGN Systematic review. SETTING Co-operation Council of the Arab States of the Gulf (GCC) states (United Arab Emirates, Bahrain, Saudi Arabia, Oman, Qatar, Kuwait). PARTICIPANTS Residents of the GCC states participating in studi...
متن کاملScreening of cardiometabolic risks clustering in young Pakistani adults classified by anthropometric traits.
OBJECTIVE To estimate frequencies of metabolic risk phenotypes and their associations in body mass index and waist circumference-based obesity categories. METHODS The cross-sectional study was conducted at Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan, from August 2014 to March 2016. Anthropometric and clinical data of young adults was collected. All subjects were catego...
متن کاملType 2 Diabetes and Heart Failure: Challenges and Solutions
Increasing numbers of older patients with type 2 diabetes, and their improved survival from cardiovascular events is seeing a massive increase in patients with both diabetes and heart failure. Already, at least a third of all patients with heart failure have diabetes. This close association is partly because all the major risk factors for heart failure also cluster in patients with type 2 diabe...
متن کاملInfluence of Haem, Non-Haem, and Total Iron Intake on Metabolic Syndrome and Its Components: A Population-Based Study
Studies suggest that haem, non-haem iron and total iron intake may be related to non-communicable diseases, especially metabolic syndrome. This study was undertaken to investigate the association of haem, non-haem iron and total iron intake with metabolic syndrome and its components. A cross-sectional population-based survey was performed in 2008, enrolling 591 adults and elderly adults living ...
متن کاملAssociation and Distribution of Hypertension, Obesity and ABO Blood groups in Blood Donors
Abstract Background Hypertension is a major health problem, especially because it has no clear symptoms. It is strongly correlated with modifiable risk factors such as adiposities, age, stress, high salt intake. Overweight and obesity is conveniently determined from BMI and visceral adiposity is determined by waist circumference. ABO blood group is one such factor which needs to be investiga...
متن کامل